This app is for use by a physician/clinician.
Serum Creatinine values can be in US Units (mg/dL) or in SI Units (μmol/L).
Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Both GFR and CCr may be estimated by formulas using just a blood test result (eGFR and eCCr).
The results of these tests are important in assessing the excretory function of the kidneys. For example, grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (or creatinine clearance).
The most advocated formula for calculating the GFR is the one that was developed by the Modification of Diet in Renal Disease Study Group.
The most commonly used formula is the "4-variable MDRD" which estimates GFR using four variables: serum creatinine, age, race, and gender. The formula underestimates the GFR in healthy patients with GFRs over 60 mL/min/1.73 m².
The NKDEP presently recommends reporting estimated GFR values greater than or equal to 60 mL/min/1.73 m2 simply as "≥60 mL/min/1.73 m2", not an exact number.
(Reference: Wikipedia, National Kidney Foundation)
NKDEP is an initiative of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), U.S. Department of Health & Human Services (DHHS).